Pryer Endoscopic Objective

The Pryer Endoscopic Objective is a powerful tool for deep tissue imaging at sub-micron resolution
Get A Quote

High-resolution deep tissue imaging without being highly invasive is difficult to achieve. Therefore, a new imaging method that allows non- or minimally-invasive image acquisition in vivo and in real time with sub-cellular spatial resolution, and at sub-second sampling rates is needed.

MCI now offers an exciting new imaging method that allows minimally- invasive image acquisition in vivo and in real time with sub-cellular spatial resolution – the MCI Pryer Endoscopic Objective (abbreviated as MCI Pryer). The MCI Pryer is a combined endoscopic objective and is compatible with any fluorescence microscopes, such as current 2P (2 photon) microscopes from Olympus and Nikon. This state-of-the-art objective allows for deep tissue access and visualisation in anaesthetised animals, awake animals with head fixation and even chronic recordings with our custom-built adaptor. If you are involved in 2 photon microscopy and 2 photon imaging then this endoscopic objective may well be perfect for you.

Image quality: Both types of Pryer lens incorporate Plan Fluoro Achromatic NIR objective.

Compatibility: The Pryer lens is compatible with all upright fluorescence microscopes including bright field microscopes, confocal, 2P and super resolution microscopes.

Can be easily integrated into most (Olympus, Nikon, etc) current 2 photon microscopes, and giving excellent spatiotemporal resolution of <0.3μm

Minimally invasive recordings from deep tissues such as brain regions (e.g. hippocampus) using anesthetized animals or awake animals that are head-fixed

Provides access to any organ or tissue from the surface to deep structures

Potential for longitudinal studies

Real-time imaging

Record dynamic changes in vivo

Can be used to study drug uptake

Easily tailored to your application and adapt to your needs

Has the potential to be used in a broad-range of applications, for instance: oncology, molecular imaging, immunology, virology, botany, etc.

Frequently Asked Questions

How deep can the Pryer objective image?

The Pryer needle-tip of the Pryer objective is 7.85 or 5.87 mm in length, depending on which magnification objective you use. And, with a working distance of 500 or 200 µm, respectively, the Pryer objectives can image deep within the brain.

Can the Pryer objective be used with a cannula?

Yes, it can. In fact we highly recommend you use a cannula to enable long-term or chronic imaging.

Can you image neuronal activity in real time with the Pryer objective?

Yes you can. The pryer objective is a great addition to your current imaging setup enabling you to image deep inside the brain and even enables you to observe activity in sub-cellular compartments, like dendrites, in real time.

Pryer Endoscopic Objective

The Pryer Endoscopic Objective is a powerful tool for deep tissue imaging at sub-micron resolution

Trusted by

Micro Control Instruments Ltd.

Innovation Stables, Unit 12 | Newplace Park | Framfield | East Sussex | TN22 5RH | United Kingdom
info@mci-neuroscience.com
Tel: +44 (0) 1825 890 858

ⒸMCI Neuroscience 2018