This Teleopto LED array system fulfills all the requirements for those wishing to perform optogenetics stimulation in vitro. It is usable for both cell and tissue cultures. Moreover, it is compatible with incubators, allowing long-term and time-controlled light stimulation of a culture.
If your are looking for a friendly ready-to-use solution, the Teleopto LED array system for optogenetics is ideal for you. This system comes complete with:
- The LED Array (LEDA-x)
- The LED Array Driver (LAD-1)
- Trigger input
The trigger input allows one to input the mode of stimulation that they desire: either constant or trigger mode. In trigger mode, one can enable time-controlled pulsed stimulation, whereas in constant mode, stimulation is constant until the trigger is switched off.
It is also possible to stimulate in vitro with more than one colour using the Two Colour LED Array (LEDA2-BY). This array emits 470nm (Blue) and 590nm (Yellow) light from the same LED. Please note that this system requires two LED Array Drivers to use it.
*the “x” in the code refers to the colour. The LED Array is available in: Violet 400nm (V), Blue 470nm (B), Green 530nm (G), Yellow 590nm (Y), Red 630nm (R) and Infrared 940nm (I).
For custom stimulation patterns, your research could benefit greatly from the TeleOpto Stimulator for Optogenetics research. See more details in the Stimulator tab to the right or give us a call at +44 1825 890 858.
There are 3 types of Teleopto LED array systems: 1 colour / 2 colours / 4 colour sections.
1 color LED array
LEDA-X. X is the colour code
The LED array system is a great solution for a variety of applications, including:
- Neuronal activity inhibition / activation (see publication in the next tab)
- Molecular biology:
Receptor directed protein expression (see publication in the next tab)
Light-regulated gene expression
- Photostimulation of proteins
- CRISPR/Cas9 gene modification
- Drug development
- Developmental biology
If you are not sure whether this would be the ideal solution for your research project, please get in touch and we will make recommendations for the most suitable options.
Thomas Westergard, Kevin McAvoy, Katelyn Russell, Xinmei Wen, Yu Pang, Brandie Morris, Piera Pasinelli, Davide Trotti, Aaron Haeusler
EMBO Mol Med. 2019 Feb; 11(2). pii: e9423. DOI: 10.15252/emmm.201809423.
Meet the NEW STO mk-II, a stimulator for Optogenetics.
This pulse generator can be connected to the TRG IN port on the LAD LED Array driver with a trigger cable. The duration and frequency of the pulses can now be controlled by TTL pulses.
Pulses are defined by the parameters depicted in the image below:
Please get in touch with our friendly applications team, for more information on this stimulator for optogenetics.
Frequently Asked Questions
With which multi-well plate is the LED Array compatible ?
The LED Array is designed for any commercial multi-well plates. It can be used with 6, 12, 24, 48 and 96 well plates.
Specifically, it fits perfectly with 96 well plates because each single LED comes just under each well.
Is the stimulator required for generating light pulses?
It depends on your use.
If you would like to illuminate your sample constantly, you can set your LED Array driver on constant mode and regulate the light intensity with the volume knob. In this situation, you don’t need the stimulator.
If you are interested in controlling the timing and duration of the light pulses, you will then require to connect the STOmk-2 stimulator to your LED Array driver.
Is the LED Array compatible with incubators?
Absolutely. The LED Array is fully waterproof and fulfills all the requirements for in-vitro experiments in incubators, such as cell culture.
Please note that the driver should not be put inside the incubator.
How do I connect the LED Array from within the incubator?
Many CO2 incubators are equipped with a cable and/or an air breathing port on the top, back or side. We recommend to use the available port to connect the LED Array to its driver.
Even if there is no cable or air breathing port, the cable of the LED Array is thin enough to come out from the gap of the front door. It can induce some slight leakage but from our experience it will not significantly affect the environment inside the incubator (temperature, humidity, CO2 concentration, etc.).
If you are unsure how to use the LED Array, please get in touch with our friendly team.
LED Array system for optogenetics
A great LED Array system, ideal for optogenetic stimulation in vitro.
Now available with TTL triggering