Image multiple areas simultaneously and in real time at sub-micron resolution. The DiveScope can be used for in vivo and in vitro imaging applications. Its small size, versatility and ease of use make it the perfect tool for the life scientist or medic.
You can use a combination of the scopes in parallel simultaneously and in real-time to deepen your understanding and advance your research of physiological systems.
Originally developed to enable deep tissue imaging of neuronal activity in the brain in vivo at sub-cellular resolution, the scope has a small cylindrical profile with a diameter of between 2 and 3 mm, depending on which system you opt for.
There are three different types of DiveScope offering different-sized fields of view, but all achieve sub-micron resolution.
Currently there are 3 types of DiveScope available. These are distinguished by their power of magnification, which affects their field of view and resolving power, make sure you choose the one that’s right for your application. And, don’t forget, you can drive two scopes from one controller.
DiveScope 12x, larger field of view (500 µm) with slightly lower resolution (0.8 µm).
DiveScope 28x, smaller field of view (200 µm) with greater resolution (0.5 µm).
DiveScope 0, our zero working distance imaging probe for clinical use.
There are two possible filter combinations for fluorescence imaging with the DiveScopes.
The dual bandpass filter sets you can choose from are:
- Green/orange: FITC (excitation max 490 nm, emission max 525 nm) / TRITC (excitation max 557 nm, emission max 576 nm).
- Green/red: FITC (excitation max 490 nm, emission max 525 nm) / TexasRed (excitation max 596 nm, emission 615 nm).
Frequently Asked Questions
How many DiveScopes can I combine in one system?
Right now, one controller can acquire from and control two DiveScopes simultaneously. This number is likely to increase as we improve our system in the future.
And, you can always use two complete systems to control up to four DiveScopes. Or incorporate a DiveScope system into your current microscopy set up as a flexible addition to your current solution.
Can I demo the DiveScope before I commit to purchasing it?
Sure! Please get in touch with us at firstname.lastname@example.org to book in a demo. We can also help with surgery training as well as providing full training in the use of the DiveScope, just ask.
What are the smallest structures I can resolve in vivo with the DiveScope?
In our hands we have been able to clearly resolve dendritic spines on fluorescent neurons in vivo, in real time, requiring no offline background image subtraction. Our microlens-based DiveScopes offer sub-micron resolution in vivo and we have tested them in multiple sites, not just deep within the brain.
Multi-channel microscopy at sub-micron resolution with our micro lens based micro endoscope and smallest epifluorescence scope on the market, the DiveScope®